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An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

January 15, 2020


Stanford University is holding a study comparing results of physicians who have undergone LASIK, SMILE, and PRK surgery. Participant physicians will first undergo an eye exam using computerized videokeratography. Those who pass the screening will, then, take a Quality of Vision Questionnaire (QoV) before surgery.


Study Information

There is an estimated enrollment of 700 participants. Participants will also be given the same Quality of Life Questionnaire three months and twelve months after surgery. They will receive a topical antibiotic for one week after surgery and orte 1% ophthalmic drops for one to four weeks after surgery.


Inclusion Criteria


All sexes, ages 21 to 52 years old, are allowed to participate. To be included in the study, participants must 

  • Be a physician or medical student.
  • Have the ability to give informed consent.
  • Speak and read English fluently.
  • Not previously had any form of refractive surgery, including prior LASIK or cataract surgery.
  • Benefit from increased spectacle independence.
  • Have been determined to be a good candidate for LASIK, SMILE or PRK procedure based on the investigator’s assessment of medical and ophthalmic health, general cognitive function, and physical and social limitations.
  • Have a treatment target of bilateral emmetropia.
  • Be willing and able to return for all follow-up examinations 


Exclusion Criteria


Those now allowed to participate are subjects who have:

  • Excessively thin corneas.
  • Topographic evidence of keratoconus.
  • Ectatic eye disorders.
  • Autoimmune diseases.
  • Current pregnancy diagnosis or nursing.



Those interested may participate in this study at Byers Eye Institute at Stanford in Palo Alto, California, 94303. Feel free to contact Linda Schwartz at 650 498-7020 with any questions or concerns.



This clinical trial is sponsored by Stanford University. The Principal Investigator is Edward E. Manche.

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